Product Datasheet
GRAMD2A antibody
Catalog Number: 31964
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q96CN5
NCBI Gene ID: NP_001012660
- Form of Antibody:
- pH7.4 PBS, 0.05% NaN3, 40% Glycerol
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Synthetic peptide of human GRAMD2A
- appl_detail:
IHC dilution:1:25-1:50
- Purification:
- Antigen affinity purification
- Background:
- Participates in the organization of endoplasmic reticulum-plasma membrane contact sites (EPCS) with pleiotropic functions including STIM1 recruitment and calcium homeostasis. Constitutive tether that co-localize with ESYT2/3 tethers at endoplasmic reticulum-plasma membrane contact sites in a phosphatidylinositol lipid-dependent manner. Pre-marks the subset of phosphtidylinositol 4,5-biphosphate (PI(4,5)P2)-enriched EPCS destined for the store operated calcium entry pathway (SOCE).
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