Product Datasheet
DMRT1 Polyclonal Antibody
Catalog Number: 31545
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9Y5R6
NCBI Gene ID:1761
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human DMRT1 (NP_068770.2).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- DMRT1; CT154; DMT1; doublesex and mab-3 related transcription factor 1
- Purification:
- Affinity purification
- Background:
- This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous.
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