Product Datasheet  
DMRT1 Polyclonal Antibody  
Catalog Number: 31545  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q9Y5R6
    NCBI Gene ID:1761
  • Form of Antibody:  
  • Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Recombinant fusion protein of human DMRT1 (NP_068770.2).
  • reactivity:  
  • Human
  • appl_detail:  
  • WB 1:500 - 1:2000
  • other_names:  
  • DMRT1; CT154; DMT1; doublesex and mab-3 related transcription factor 1
  • Purification:  
  • Affinity purification
  • Specificity:  
  • Applications:  
  • WB
  • Background:  
  • This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous.



 
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