Product Datasheet
EME1 Polyclonal Antibody
Catalog Number: 31531
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q96AY2
NCBI Gene ID:146956
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human EME1 (NP_689676.2).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- EME1; MMS4L; SLX2A; crossover junction endonuclease EME1
- Purification:
- Affinity purification
- Background:
- This gene encodes a protein that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. This protein may be involved in repairing DNA damage and in maintaining genomic stability. Alternative splicing results in multiple transcript variants.
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