Product Datasheet
NR1H4 Polyclonal Antibody
Catalog Number: 31507
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q96RI1
NCBI Gene ID:9971
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human NR1H4 (NP_001193908.1).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- NR1H4; BAR; FXR; HRR-1; HRR1; PFIC5; RIP14; bile acid receptor
- Purification:
- Affinity purification
- Background:
- This gene encodes a ligand-activated transcription factor that shares structural features in common with nuclear hormone receptor family members. This protein functions as a receptor for bile acids, and when bound to bile acids, binds to DNA and regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described.
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