Product Datasheet
DOCK8 Polyclonal Antibody
Catalog Number: 31410
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q8NF50
NCBI Gene ID:81704
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human DOCK8 (NP_982272.2).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- DOCK8; HEL-205; MRD2; ZIR8; dedicator of cytokinesis 8
- Purification:
- Affinity purification
- Background:
- This gene encodes a member of the DOCK180 family of guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with Rho GTPases and are components of intracellular signaling networks. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.
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