Product Datasheet
GUCA1A Polyclonal Antibody
Catalog Number: 31302
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P43080
NCBI Gene ID:2978
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human GUCA1A (NP_000400.2).
- appl_detail:
- WB 1:500 - 1:2000
IHC 1:50 - 1:200
- other_names:
- GUCA1A; C6orf131; COD3; CORD14; GCAP; GCAP1; GUCA; GUCA1; guanylate cyclase activator 1A
- Purification:
- Affinity purification
- Background:
- This gene encodes an enzyme that plays a role in the recovery of retinal photoreceptors from photobleaching. This enzyme promotes the activity of retinal guanylyl cyclase-1 (GC1) at low calcium concentrations and inhibits GC1 at high calcium concentrations. Mutations in this gene can cause cone dystrophy 3 and code-rod dystrophy 14. Alternative splicing results in multiple transcript variants.
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