Product Datasheet  
STX1A Antibody  
Catalog Number: 31295  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:Q16623
    Gene ID:6804
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C/1 year
  • Immunogen:  
  • Synthetic peptide corresponding to a region derived from 1-15 amino acids of human syntaxin 1A (brain)
  • reactivity:  
  • Hu Ms Rt
  • appl_detail:  
  • Predicted MW: 33kd
    ELISA: 1:2000-1:10000
    Western blotting: 1:1000-1:5000
    Immunohistochemistry: 1:50-1:200

  • other_names:  
  • Syntaxin 1A (brain), STX1; HPC-1; P35-1; SYN1A
  • Purification:  
  • Specificity:  
  • The antibody detects endogenous level of total STX1A protein.
  • Applications:  
  • ELISA WB IHC
  • Background:  
  • This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.




 
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