Product Datasheet
YWHAQ Antibody
Catalog Number: 31247
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:O43639
Gene ID:8440
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Synthetic peptide corresponding to a region derived from 140-154 amino acids of Human tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
- other_names:
- tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide, 1C5, HS1, 14-3-3
- Specificity:
- The antibody detects endogenous level of total YWHAQ protein.
- Applications:
- ELISA WB IHC
- Background:
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.?
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