Product Datasheet  
MMP8 Antibody  
Catalog Number: 31238  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q99542
    Gene ID:4327
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Synthetic peptide corresponding to a region derived from 122-135 amino acids of human matrix metallopeptidase 8 (neutrophil collagenase)
  • reactivity：  
  • Hu
  • appl_detail：  

  • Predicted MW: 53kd
    ELISA: 1:2000-1:5000
    Western blotting: 1:500-1:2000
    Immunohistochemistry: 1:25-1:100

  • other_names：  
  • matrix metallopeptidase 8 (neutrophil collagenase), HNC, CLG1, MMP-8, PMNL-CL
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total MMP8 protein.
  • Applications：  
  • ELISA WB IHC
  • Background：  

  • Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.




 
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