Product Datasheet  
IL15RA Antibody  
Catalog Number: 31223  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q6ISS4
    Gene ID:3904
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Synthetic peptide corresponding to a region derived from 250-264 amino acids of Human interleukin 15 receptor, alpha
  • reactivity：  
  • Hu
  • appl_detail：  

  • Predicted MW: 28kd
    ELISA: 1:1000-1:5000
    Western blotting: 1:1000-1:5000

  • other_names：  
  • interleukin 15 receptor, alpha, CD215
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total IL15RA protein.
  • Applications：  
  • ELISA WB
  • Background：  

  • This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.




 
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