Product Datasheet  
HDAC3 Antibody  
Catalog Number: 31216  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:O15347
    Gene ID:3149
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Synthetic peptide corresponding to a region derived from 414-428 amino acids of Human histone deacetylase 3
  • reactivity：  
  • Hu Rt
  • appl_detail：  

  • Predicted MW: 49kd
    ELISA: 1:1000-1:5000
    Western blotting: 1:500-1:2000

  • other_names：  
  • histone deacetylase 3, HD3, RPD3, RPD3-2
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total HDAC3 protein.
  • Applications：  
  • ELISA WB
  • Background：  

  • Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.




 
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