Product Datasheet  
CLDN1 Antibody  
Catalog Number: 31203  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:O00451
    Gene ID:2675
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Synthetic peptide corresponding to a region derived from 196-209 amino acids of Human claudin 1
  • reactivity：  
  • Hu
  • appl_detail：  

  • Predicted MW: 23kd
    ELISA: 1:1000-1:10000
    Western blotting: 1:2000-1:5000
    Immunohistochemistry: 1:100-1:300

  • other_names：  
  • claudin 1, CLD1, SEMP1, ILVASC
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total CLDN1 protein.
  • Applications：  
  • ELISA WB IHC
  • Background：  

  • Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.




 
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