Product Datasheet  
DISC1 Antibody  
Catalog Number: 31185  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:P48664
    Gene ID:6511
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Synthetic peptide corresponding to a region derived from 737-750 amino acids of Human disrupted in schizophrenia 1
  • reactivity：  
  • Hu
  • appl_detail：  

  • Predicted MW: 60kd
    ELISA: 1:1000-1:5000
    Western blotting: 1:1000-1:5000
    Immunohistochemistry: 1:50-1:200

  • other_names：  
  • disrupted in schizophrenia 1, SCZD9, C1orf136
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total DISC1 protein.
  • Applications：  
  • ELISA WB IHC
  • Background：  

  • This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.




 
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