Product Datasheet  
F3 Antibody  
Catalog Number: 31131  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q9Y4K3
    Gene ID:7189
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Fusion protein corresponding to a region derived from 33-251 amino acids of human coagulation factor III (thromboplastin, tissue factor)
  • reactivity：  
  • Hu
  • appl_detail：  

  • Predicted MW: 33kd
    ELISA: 1:1000-1:2000
    Western blotting: 1:200-1:1000
    Immunohistochemistry: 1:25-1:100

  • other_names：  
  • Coagulation factor III (thromboplastin, tissue factor), TF; TFA; CD142
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total F3 protein.
  • Applications：  
  • ELISA WB IHC
  • Background：  

  • This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.




 
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