Product Datasheet
PARK7 Antibody
Catalog Number: 31108
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P11498
Gene ID:5091
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Full length fusion protein
- other_names:
- parkinson protein 7, DJ1, DJ-1
- Specificity:
- The antibody detects endogenous level of total PARK7 protein.
- Applications:
- ELISA WB IHC
- Background:
The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.
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