Product Datasheet
MAGED1 Antibody
Catalog Number: 31097
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P51511
Gene ID:4324
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Fusion protein corresponding to C terminal 300 amino acids of human melanoma antigen family D, 1
- appl_detail:
- Predicted MW: 86kd
ELISA: 1:2000-1:5000
Western blotting: 1:500-1:2000
- other_names:
- melanoma antigen family D, 1, NRAGE, DLXIN-1
- Specificity:
- The antibody detects endogenous level of total MAGED1 protein.
- Background:
- This gene is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. This gene has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms have been found for this gene.
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