Product Datasheet  
BIRC7 Antibody  
Catalog Number: 31094  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Genbank No.: BC014475
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Full length fusion protein
  • reactivity：  
  • Hu
  • appl_detail：  
  • Predicted MW: 33kd
    ELISA: 1:2000-1:5000
    Western blotting: 1:500-1:2000
    Immunohistochemistry: 1:10-1:50
  • other_names：  
  • baculoviral IAP repeat containing 7, KIAP, LIVIN, MLIAP, RNF50, ML-IAP
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total BIRC7 protein.
  • Applications：  
  • ELISA WB IHC
  • Background：  
  • The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide.?



 
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