Product Datasheet  
COPS5 Antibody  
Catalog Number: 31092  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q969P5
    Gene ID:114907
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Full length fusion protein
  • reactivity：  
  • Hu Ms
  • appl_detail：  

  • Predicted MW: 38kd
    ELISA: 1:2000-1:10000
    Western blotting: 1:1000-1:5000
    Immunohistochemistry: 1:150-1:500

  • other_names：  
  • COP9 constitutive photomorphogenic homolog subunit 5, CSN5, JAB1, SGN5, MOV-34
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total COPS5 protein.
  • Applications：  
  • ELISA WB IHC
  • Background：  

  • The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors




 
© Signalway Biotechnology All Rights Reserved.