Product Datasheet  
FHIT Antibody  
Catalog Number: 31073  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:P32298
    Gene ID:2868
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Full length fusion protein
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Predicted MW: 17kd
    ELISA: 1:1000-1:5000
    Western blotting: 1:500-1:2000
    Immunohistochemistry: 1:25-1:100
  • other_names：  
  • fragile histidine triad, FRA3B, AP3Aase
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total FHIT protein.
  • Applications：  
  • ELISA WB IHC
  • Background：  
  • This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene.



 
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