Product Datasheet
CBX2 Antibody
Catalog Number: 31050
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q00535
Gene ID:1020
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Full length fusion protein
- appl_detail:
- Predicted MW: 23kd
ELISA: 1:1000-1:5000
Western blotting: 1:500-1:2000
- other_names:
- chromobox homolog 2, M33, CDCA6, SRXY5
- Specificity:
- The antibody detects endogenous level of total CBX2 protein.
- Background:
- This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in mice results in male-to-female gonadal sex reversal. Mutations in this gene are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
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