Product Datasheet
BID Antibody
Catalog Number: 31037
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P04632
Gene ID:826
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Full length fusion protein
- appl_detail:
- Predicted MW: 22kd
ELISA: 1:1000-1:5000
Western blotting: 1:200-1:2000
Immunohistochemistry: 1:25-1:100
- other_names:
- BH3-interacting domain death agonist, FP497
- Specificity:
- The antibody detects endogenous level of total BID protein.
- Applications:
- ELISA WB IHC
- Background:
- This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
© Signalway Biotechnology All Rights Reserved.