Product Datasheet
KRT5 Antibody
Catalog Number: 31032
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P02766
Gene ID:7276
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Fusion protein corresponding to a region derived from 203-477 amino acids of Human Keratin, type II cytoskeletal 5
- appl_detail:
- Predicted MW: 62kd
ELISA: 1:1000-1:5000
Western blotting: 1:500-1:2000
- other_names:
- Keratin, type II cytoskeletal 5, K5, CK5, DDD, EBS2, KRT5A
- Specificity:
- The antibody detects endogenous level of total KRT5 protein.
- Background:
- The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
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