Product Datasheet  
AK1 Antibody  
Catalog Number: 31027  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:P08133
    Gene ID:309
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Fusion protein corresponding to a region derived from 1-194 amino acids of Human Adenylate kinase isoenzyme 1
  • reactivity：  
  • Hu
  • appl_detail：  

  • Predicted MW: 22kd
    ELISA: 1:2000-1:5000
    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:25-1:100

  • other_names：  
  • Adenylate kinase isoenzyme 1 ,
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total AK1 protein.
  • Applications：  
  • ELISA WB IHC
  • Background：  

  • Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.




 
© Signalway Biotechnology All Rights Reserved.