Product Datasheet  
IL18BP Antibody  
Catalog Number: 31022  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:O95831
    Gene ID:9131
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Fusion protein corresponding to a region derived from 31-195 of human Interleukin-18-binding protein
  • reactivity：  
  • Hu
  • appl_detail：  

  • Predicted MW: 21kd
    ELISA: 1:1000-1:5000
    Western blotting: 1:500-1:2000

  • other_names：  
  • interleukin 18 binding protein, IL18BPa
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total IL18BP protein.
  • Applications：  
  • ELISA WB
  • Background：  

  • The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.




 
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