Product Datasheet
LMO1 Polyclonal Antibody
Catalog Number: 30963
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P25800
NCBI Gene ID:4004
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human LMO1 (NP_002306.1).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- LMO1; RBTN1; RHOM1; TTG1; rhombotin-1
- Purification:
- Affinity purification
- Background:
- This locus encodes a transcriptional regulator that contains two cysteine-rich LIM domains but lacks a DNA-binding domain. LIM domains may play a role in protein interactions; thus the encoded protein may regulate transcription by competitively binding to specific DNA-binding transcription factors. Alterations at this locus have been associated with acute lymphoblastic T-cell leukemia. Chromosomal rearrangements have been observed between this locus and at least two loci, the delta subunit of the T-cell antigen receptor gene and the LIM domain binding 1 gene. Alternatively spliced transcript variants have been described.
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