Product Datasheet
TBCE Polyclonal Antibody
Catalog Number: 30929
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q15813
NCBI Gene ID:6905
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human TBCE (NP_003184.1).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- TBCE; HRD; KCS; KCS1; PEAMO; pac2; tubulin folding cofactor E
- Purification:
- Affinity purification
- Background:
- Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. Two transcript variants encoding the same protein have been found for this gene.
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