Product Datasheet  
NSL1 Polyclonal Antibody  
Catalog Number: 30815  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q96IY1
    NCBI Gene ID:25936
  • Form of Antibody:  
  • Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Recombinant fusion protein of human NSL1 (NP_056286.3).
  • reactivity:  
  • Human
  • appl_detail:  
  • WB 1:500 - 1:2000
    IF 1:50 - 1:100
  • other_names:  
  • NSL1; C1orf48; DC8; MIS14; NSL1, MIS12 kinetochore complex component
  • Purification:  
  • Affinity purification
  • Specificity:  
  • Applications:  
  • WB,IF
  • Background:  
  • This gene encodes a protein with two coiled-coil domains that localizes to kinetochores, which are chromosome-associated structures that attach to microtubules and mediate chromosome movements during cell division. The encoded protein is part of a conserved protein complex that includes two chromodomain-containing proteins and a component of the outer plate of the kinetochore. This protein complex is proposed to bridge centromeric heterochromatin with the outer kinetochore structure. Multiple transcript variants encoding different isoforms have been found for this gene. There is a pseudogene of the 3' UTR region of this gene on chromosome X.



 
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