Product Datasheet  
ERCC8 Polyclonal Antibody  
Catalog Number: 30744  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q13216
    NCBI Gene ID:1161
  • Form of Antibody：  
  • Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • A synthetic synthetic peptide of human ERCC8 (NP_000073.1).
  • reactivity：  
  • Mouse
  • appl_detail：  
  • WB 1:500 - 1:2000
  • other_names：  
  • ERCC8; CKN1; CSA; UVSS2; DNA excision repair protein ERCC-8
  • Purification：  
  • Affinity purification
  • Specificity：  
  • Applications：  
  • WB
  • Background：  
  • This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes. Several transcript variants encoding different isoforms have been found for this gene.



 
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