Product Datasheet
PDLIM3 Polyclonal Antibody
Catalog Number: 30714
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q53GG5
NCBI Gene ID:27295
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human PDLIM3 (NP_001107579.1).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- PDLIM3; ALP; PDZ and LIM domain 3
- Purification:
- Affinity purification
- Background:
- The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy.
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