Product Datasheet
ETF1 Polyclonal Antibody
Catalog Number: 30673
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P62495
NCBI Gene ID:2107
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human ETF1 (NP_004721.1).
- reactivity:
- Human,Mouse,Rat
- appl_detail:
- WB 1:200 - 1:2000
IF 1:50 - 1:200
- other_names:
- ETF1; D5S1995; ERF; ERF1; RF1; SUP45L1; TB3-1; eukaryotic translation termination factor 1
- Purification:
- Affinity purification
- Background:
- This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 6, 7, and X.
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