Product Datasheet
CMA1 Polyclonal Antibody
Catalog Number: 30660
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P23946
NCBI Gene ID:1215
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human CMA1 (NP_001827.1).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- CMA1; CYH; MCT1; chymase
- Purification:
- Affinity purification
- Background:
- This gene encodes a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Alternative splicing results in multiple variants.
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