Product Datasheet
FBXL5 Polyclonal Antibody
Catalog Number: 30657
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9UKA1
NCBI Gene ID:26234
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human FBXL5 (NP_036293.1).
- reactivity:
- Human,Mouse,Rat
- appl_detail:
- WB 1:500 - 1:1000
IHC 1:50 - 1:100
- other_names:
- FBXL5; FBL4; FBL5; FLR1; F-box/LRR-repeat protein 5
- Purification:
- Affinity purification
- Background:
- This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats. Alternatively spliced transcript variants have been described for this locus.
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