Product Datasheet  
Acetyl-DNMT1-K1127/K1129/K1131/K1133 pAb  
Catalog Number: 30656  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P26358
    NCBI Gene ID:1786
  • Form of Antibody：  
  • Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • A synthetic peptide of human DNMT1
  • reactivity：  
  • Human,Mouse,Rat
  • appl_detail：  
  • IHC 1:50 - 1:100
    IF 1:50 - 1:100
  • other_names：  
  • DNMT1; ADCADN; AIM; CXXC9; DNMT; HSN1E; MCMT; m.HsaI; DNA methyltransferase 1
  • Purification：  
  • Affinity purification
  • Specificity：  
  • Applications：  
  • IHC,IF
  • Background：  
  • This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.



 
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