1-832-868-1888
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Catalog Number: |
30513 |
| other_names: | PMM2; CDG1; CDG1a; CDGS; PMI; PMI1; PMM 2; phosphomannomutase 2 |
Amount: |
100μg |
| calculated_mw: | 28kDa |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#:O15305 |
Form of Antibody: |
Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4. |
Storage/Stability: |
|
Immunogen: |
Recombinant fusion protein of human PMM2 (NP_000294.1). |
Purification: |
Affinity purification |
Specificity/Sensitivity: |
|
Applications: |
WB,IHC,IF |
Background: |
The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. Mutations in this gene have been shown to cause defects in glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein syndrome type I. |
References: |
|
appl_detail: |
WB 1:500 - 1:2000 |
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