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NSUN2 Polyclonal Antibody

Catalog Number:

30455
other_names: NSUN2; MISU; MRT5; SAKI; TRM4; tRNA (cytosine(34)-C(5))-methyltransferase

Amount:

100μg
calculated_mw: 105kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q08J23
NCBI Gene ID:54888

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human NSUN2 (NP_060225.4).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC,IF

Background:

This gene encodes a methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. This modification is necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200

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