CD8B Polyclonal Antibody

Catalog Number:

30440

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P10966
NCBI Gene ID:926

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human CD8B (NP_757362.1).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF