FLNB Polyclonal Antibody

Catalog Number:

30419

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:O75369
NCBI Gene ID:2317

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human FLNB (NP_001157789.1).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC,IF

Background:

This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3; boomerang dysplasia; autosomal dominant Larsen syndrome; and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

References:

appl_detail:

WB 1:500 - 1:1000
IHC 1:50 - 1:100
IF 1:20 - 1:100

Datasheet PDF