STK4 Polyclonal Antibody

Catalog Number:

30303

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q13043
NCBI Gene ID:6789

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human STK4 (NP_006273.1).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC

Background:

The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:200
IP 1:20 - 1:50

Datasheet PDF