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MRPL48 Polyclonal Antibody

Catalog Number:

30040
other_names: L48MT; CGI-118; HSPC290; MRP-L48

Amount:

100μg
calculated_mw: Refer to figures
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q96GC5
NCBI Gene ID:51642

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant protein of human MRPL48.

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 6p. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene.

References:

appl_detail:

WB 1:500 - 1:2000

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