KCNA4 Polyclonal Antibody

Catalog Number:

29829

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P22459
NCBI Gene ID:3739

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

A synthetic peptide of human KCNA4 (NP_002224.1).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the A-type potassium current class, the members of which may be important in the regulation of the fast repolarizing phase of action potentials in heart and thus may influence the duration of cardiac action potential.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF