ERCC6 Polyclonal Antibody

Catalog Number:

30363

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q03468
NCBI Gene ID:2074

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant protein of human ERCC6.

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

IHC

Background:

This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The encoded protein has ATP-stimulated ATPase activity, interacts with several transcription and excision repair proteins, and may promote complex formation at DNA repair sites. Mutations in this gene are associated with Cockayne syndrome type B and cerebrooculofacioskeletal syndrome 1. Alternative splicing occurs between a splice site from exon 5 of this gene to the 3' splice site upstream of the open reading frame (ORF) of the adjacent gene, piggyback-derived-3 (GeneID:267004), which activates the alternative polyadenylation site downstream of the piggyback-derived-3 ORF. The resulting transcripts encode a fusion protein that shares sequence with the product of each individual gene.

References:

appl_detail:

IHC 1:50 - 1:200

Datasheet PDF