MED7 Polyclonal Antibody

Catalog Number:

29718

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:O43513
NCBI Gene ID:9443

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human MED7 (NP_004261.1).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Two transcript variants encoding the same protein have been found for this gene.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF