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Catalog Number: |
29546 |
| other_names: | MAP3K1; MAPKKK1; MEKK; MEKK 1; MEKK1; SRXY6; mitogen-activated protein kinase kinase kinase 1 |
Amount: |
100μg |
| calculated_mw: | 164kDa |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#:Q13233 |
Form of Antibody: |
Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4. |
Storage/Stability: |
|
Immunogen: |
A synthetic synthetic peptide of human MAP3K1 (NP_005912.1). |
Purification: |
Affinity purification |
Specificity/Sensitivity: |
|
Applications: |
WB,IHC,IF |
Background: |
The protein encoded by this gene is a serine/threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF-kappa-B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus. |
References: |
|
appl_detail: |
WB 1:500 - 1:2000 |
QUICK LINKS
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