MAFG Polyclonal Antibody

Catalog Number:

29545

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:O15525
NCBI Gene ID:4097

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human MAFG (NP_002350.1).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

Globin gene expression is regulated through nuclear factor erythroid-2 (NFE2) elements located in enhancer-like locus control regions positioned many kb upstream of alpha- and beta-gene clusters (summarized by Blank et al., 1997 [PubMed 9166829]). NFE2 DNA-binding activity consists of a heterodimer containing a ubiquitous small Maf protein (MafF, MIM 604877; MafG; or MafK, MIM 600197) and the tissue-restricted protein p45 NFE2 (MIM 601490). Both subunits are members of the activator protein-1-like superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160).

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF