FBXW2 Polyclonal Antibody

Catalog Number:

29532

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9UKT8
NCBI Gene ID:26190

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human FBXW2 (NP_036296.2).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF