KIF7 Polyclonal Antibody

Catalog Number:

29353

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q2M1P5
NCBI Gene ID:374654

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human KIF7 (NP_940927.2).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.

References:

appl_detail:

WB 1:200 - 1:2000

Datasheet PDF