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GSK3 alpha/beta Antibody

Catalog Number:

29039
other_names: DKFZp686D0638; glycogen synthase kinase 3 alpha; Glycogen synthase kinase-3 alpha; GSK-3 alpha; GSK3A

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P49840

Form of Antibody:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

A synthesized peptide derived from human GSK3 alpha/beta

Purification:

Immunogen affinity purified

Specificity/Sensitivity:

GSK3 alpha/beta Antibody detects endogenous levels of total GSK3 alpha/beta

Applications:

WB IHC

Background:

 GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase.

References:

appl_detail:

WB: 1:500-1:2000 

IHC: 1:50-1:200

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