Cleaved-PARP antibody

Catalog Number:

29033

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P09874

Form of Antibody:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 14 months from date of receipt

Storage/Stability:

Immunogen:

Purification:

Immunogen affinity purified

Specificity/Sensitivity:

PARP (Cleaved-Asp214) Antibody detects endogenous levels of fragment of activated PARP resulting from cleavage adjacent to Asp214.

Applications:

WB

Background:

 Nvolved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.

References:

appl_detail:

 WB: 1:500-1:2000

Datasheet PDF