MYOF Polyclonal Antibody

Catalog Number:

28961

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9NZM1
NCBI Gene ID:26509

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human MYOF (NP_038479.1).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined.

References:

appl_detail:

WB 1:200 - 1:2000

Datasheet PDF