RASGRP2 Polyclonal Antibody

Catalog Number:

28939

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q7LDG7
NCBI Gene ID:10235

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human RASGRP2 (NP_722541.1).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Four alternatively spliced transcript variants encoding two different isoforms have been found for this gene.

References:

appl_detail:

WB 1:200 - 1:2000

Datasheet PDF